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Article

brinker is a target of Dpp in Drosophila that negatively regulates Dpp-dependent genes.

Nature - 18 Mar 1999

Minami M, Kinoshita N, Kamoshida Y, Tanimoto H, Tabata T

Abstract excerpt

Growth and patterning of the Drosophila wing is controlled in part by the long-range organizing activities of the Decapentaplegic protein (Dpp). Dpp is synthesized by cells that line the anterior side of the anterior/posterior compartment border of the wing imaginal disc. From this source, Dpp is thought to generate a concentration gradient that patterns both anterior and posterior compartments. Among the gene...

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Identifiers

PMID: 10094047
DOI: 10.1038/18451

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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brinker is a target of Dpp in Drosophila that negatively regulates Dpp-dependent genes.PMID 10094047Read ↗

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The T-box-encoding Dorsocross genes function in amnioserosa development and the patterning of the dorsolateral germ band downstream of Dpp.Semantic proximity Read ↗

Growth regulation by Dpp: an essential role for Brinker and a non-essential role for graded signaling levels.Semantic proximity Read ↗

The transcription factor optomotor-blind antagonizes Drosophila haltere growth by repressing decapentaplegic and hedgehog targets.Semantic proximity Read ↗

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