Groucho mediates a Ci-independent mechanism of hedgehog repression in the anterior wing pouch.

doi:10.1242/dev.128.21.4361

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Groucho mediates a Ci-independent mechanism of hedgehog repression in the anterior wing pouch.

Development (Cambridge, England) - 1 Nov 2001

Apidianakis Y, Grbavec D, Stifani S, Delidakis C

Abstract excerpt

Groucho (Gro) is the founding member of a family of transcriptional co-repressors that are recruited by a number of different transcription factors. Drosophila has a single gro gene, whose loss of function affects processes ranging from sex determination to embryonic patterning and neuroblast specification. We have characterized a function of Gro in imaginal development, namely the repression of hedgehog (hh) in...

Topics

Animals
Animals, Genetically Modified
Basic Helix-Loop-Helix Transcription Factors
DNA-Binding Proteins
Drosophila
Drosophila Proteins
Gene Expression Regulation, Developmental
Hedgehog Proteins
Insect Proteins
Larva
Mutation
Repressor Proteins
Transcription Factors
Wings, Animal

Source

Open in PubMed

Identifiers

PMID: 11684670
DOI: 10.1242/dev.128.21.4361

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics