Article
Chemical modification of a variant of human MIP-1alpha; implications for dimer structure.
Protein science : a publication of the Protein Society - 1 Oct 2000
Ashfield J T, Meyers T, Lowne D, Varley P G, Arnold J R, Tan P, Yang J C, Czaplewski L G, Dudgeon T, Fisher J
Abstract excerpt
A sequence variant of human MIP-1alpha, in which Asp26 has been replaced by Al alpha, has been chemically modified by the addition of 13C-labeled methyl groups at each of the lysine residues and the N-terminus. The sites of methylation have been verified by a combination of MALDI-TOF mass spectrometric experiments and tryptic digestion followed by N-terminal mapping. The effect of the modification on the...
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