Article
The androgen receptor transactivation domain: the interplay between protein conformation and protein-protein interactions.
Biochemical Society transactions - 1 Oct 2003
Reid J, Betney R, Watt K, McEwan I J
Abstract excerpt
The AR (androgen receptor) belongs to the nuclear receptor superfamily and directly regulates patterns of gene expression in response to the steroids testosterone and dihydrotestosterone. Sequences within the large N-terminal domain of the receptor have been shown to be important for transactivation and protein-protein interactions; however, little is known about the structure and folding of this region. Folding...
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