Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HSNF5/INI1 gene mutations in lymphoid malignancy.

Cancer genetics and cytogenetics - 1 Oct 2000

Yuge M, Nagai H, Uchida T, Murate T, Hayashi Y, Hotta T, Saito H, Kinoshita T

Abstract excerpt

hSNF5/INI1 is one of the components of the SWI/SNF multiprotein complex that is necessary for the transcriptional activation of several genes and functions by altering chromatin structure. This gene has been thought to be one of the tumor suppressor genes (TSGs) because deletions or mutations were reported in malignant rhabdoid tumors and atypical teratoid and rhabdoid tumors. To evaluate the hSNF5/INI1 gene as a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomal Proteins, Non-Histone
Share to DNA Primers
Share to Lymphoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multiple Myeloma

Share to Polymorphism, Single-Stranded Conformational

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to SMARCB1 Protein

Source

Identifiers

PMID: 11104031
DOI: 10.1016/s0165-4608(00)00274-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HSNF5/INI1 gene mutations in lymphoid malignancy.PMID 11104031Read ↗

Aberrations of the hSNF5/INI1 gene are restricted to malignant rhabdoid tumors or atypical teratoid/rhabdoid tumors in pediatric solid tumors.Semantic proximity Read ↗

Integrase interactor 1 in health and disease.Semantic proximity Read ↗

Spectrum of hSNF5/INI1 somatic mutations in human cancer and genotype-phenotype correlations.Semantic proximity Read ↗

hSNF5 /INI1 mutation analysis in acute myeloid leukemia.Semantic proximity Read ↗

Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer.Semantic proximity Read ↗

Alterations of the hSNF5/INI1 gene in central nervous system atypical teratoid/rhabdoid tumors and renal and extrarenal rhabdoid tumors.Semantic proximity Read ↗

INI1-Deficient TumorsSemantic proximity Read ↗

c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function.Semantic proximity Read ↗

Mutations of the hSNF5/INI1 gene in renal rhabdoid tumors with second primary brain tumors.Semantic proximity Read ↗

Immunohistochemical analysis of hSNF5/INI1 in pediatric CNS neoplasms.Semantic proximity Read ↗

A key role of the hSNF5/INI1 tumour suppressor in the control of the G1-S transition of the cell cycle.Semantic proximity Read ↗

Haploinsufficiency of Snf5 (integrase interactor 1) predisposes to malignant rhabdoid tumors in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.