Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional analysis of human ornithine decarboxylase alleles.

Cancer research - 15 Nov 2000

Guo Y, Harris R B, Rosson D, Boorman D, O'Brien T G

Abstract excerpt

It has been known for > 10 years that there are two alleles of the human ornithine decarboxylase (ODC) gene, defined by a polymorphic PstI RFLP in intron 1. We have sequenced a large portion of each of the two alleles, including some of the 5' promoter region, exon 1, intron 1, and exon 2, and determined that a single nucleotide polymorphism at base +317 (relative to transcription start site) is responsible for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3T3 Cells
Share to Colon
Share to Intestinal Mucosa

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Leukocytes

Share to Neoplasms

Share to Ornithine Decarboxylase

Share to Polymorphism, Restriction Fragment Length

Share to Transfection

Source

Identifiers

PMID: 11103791

Genes

MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional analysis of human ornithine decarboxylase alleles.PMID 11103791Read ↗

Differences in ornithine decarboxylase and androgen receptor allele frequencies among ethnic groups.Semantic proximity Read ↗

Polymorphisms in the human ornithine transcarbamylase gene useful for allele tracking. Mutations in brief no. 193. Online.Semantic proximity Read ↗

Strong bias in the location of functional promoter polymorphisms.Semantic proximity Read ↗

The analysis of GSTA1 promoter genetic and functional diversity of human populations.Semantic proximity Read ↗

Disease-causing mutations in the promoter and enhancer of the ornithine transcarbamylase gene.Semantic proximity Read ↗

Disruption of OTC promoter-enhancer interaction in a patient with symptoms of ornithine carbamoyltransferase deficiency.Semantic proximity Read ↗

A promoter variant in the OTC gene associated with late and variable age of onset hyperammonemia.Semantic proximity Read ↗

A negative regulatory element within the proximal promoter region of the rat ornithine decarboxylase gene.Semantic proximity Read ↗

Mutations and polymorphisms in the human ornithine transcarbamylase gene: mutation update addendum.Semantic proximity Read ↗

Associations of a polymorphism in the ornithine decarboxylase gene with colorectal cancer survival.Semantic proximity Read ↗

Human polymorphic variants of the NEIL1 DNA glycosylase.Semantic proximity Read ↗

Genetic polymorphism in ornithine decarboxylase and risk of breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.