Article
Differences in ornithine decarboxylase and androgen receptor allele frequencies among ethnic groups.
Molecular carcinogenesis - 1 Oct 2004
O'Brien Thomas G, Guo Y, Visvanathan K, Sciulli J, McLaine M, Helzlsouer K J, Watkins-Bruner D
Abstract excerpt
Recent evidence suggests that the A allele of the ornithine decarboxylase (ODC) gene is a genetic risk factor for prostate cancer. ODC is a target gene of the highly polymorphic androgen receptor (AR) gene, short alleles of which have been associated in some studies with increased prostate cancer risk. We determined ODC allele frequencies and distribution of AR alleles in American Caucasians, African-Americans,...
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