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Article

Crystal structure of a nucleosome core particle containing the variant histone H2A.Z.

Nature structural biology - 1 Dec 2000

Suto R K, Clarkson M J, Tremethick D J, Luger K

Abstract excerpt

Activation of transcription within chromatin has been correlated with the incorporation of the essential histone variant H2A.Z into nucleosomes. H2A.Z and other histone variants may establish structurally distinct chromosomal domains; however, the molecular mechanism by which they function is largely unknown. Here we report the 2.6 A crystal structure of a nucleosome core particle containing the histone variant...

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Identifiers

PMID: 11101893
DOI: 10.1038/81971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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