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Article

Identification of the collagen-binding site of the von Willebrand factor A3-domain.

The Journal of biological chemistry - 30 Mar 2001

Romijn R A, Bouma B, Wuyster W, Gros P, Kroon J, Sixma J J, Huizinga E G

Abstract excerpt

Von Willebrand factor (vWF) is a multimeric glycoprotein that mediates platelet adhesion and thrombus formation at sites of vascular injury. vWF functions as a molecular bridge between collagen and platelet receptor glycoprotein Ib. The major collagen-binding site of vWF is contained within the A3 domain, but its precise location is unknown. To localize the collagen-binding site, we determined the crystal...

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Source

Identifiers

PMID: 11098050
DOI: 10.1074/jbc.M006548200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Identification of the collagen-binding site of the von Willebrand factor A3-domain.PMID 11098050Read ↗

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