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Article

A structure of a collagen VI VWA domain displays N and C termini at opposite sides of the protein.

Structure (London, England : 1993) - 4 Feb 2014

Becker Ann-Kathrin A, Mikolajek Halina, Paulsson Mats, Wagener Raimund, Werner Jörn M

Abstract excerpt

Von Willebrand factor A (VWA) domains are versatile protein interaction domains with N and C termini in close proximity placing spatial constraints on overall protein structure. The 1.2 Å crystal structures of a collagen VI VWA domain and a disease-causing point mutant show C-terminal extensions that place the N and C termini at opposite ends. This allows a "beads-on-a-string" arrangement of multiple VWA domains...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24332716
DOI: 10.1016/j.str.2013.06.028
PMCID: PMC3919171

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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