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Article

[Individualization of drug therapy and pharmacogenetics].

Nihon rinsho. Japanese journal of clinical medicine - 1 Mar 1998

Yamamoto I, Azuma J

Abstract excerpt

This brief review discusses the relationship between genetic polymorphism of drug metabolizing enzyme and drug's safety and efficacy. When elimination occurs via a single metabolic pathway, individual differences in metabolic rates can lead to large differences in drug and metabolite concentrations in the blood. Genetic polymorphism leads to subpopulation of patients with decreased, absent or even increased...

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Share to Arylamine N-Acetyltransferase
Share to Cytochrome P-450 CYP2D6
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9549339

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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