Article
TAP1 and TAP2 polymorphism in Spanish patients with ankylosing spondylitis.
Experimental and clinical immunogenetics - 1 Jan 2000
Fraile A, Collado M D, Matarán L, Martín J, Nieto A
Abstract excerpt
OBJECTIVE: HLA-B27 is strongly associated with ankylosing spondylitis (AS); however, the association is not absolute and additional susceptibility factors in the MHC region could play a role. We studied the influence of polymorphism in the transporter associated with antigen processing (TAP) genes, including point mutations not previously analyzed. METHODS: HLA-B*27 typing and subtyping as well as TAP1 and TAP2...
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