TAP1 and TAP2 polymorphism in Spanish patients with ankylosing spondylitis.

doi:10.1159/000019139

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

TAP1 and TAP2 polymorphism in Spanish patients with ankylosing spondylitis.

Experimental and clinical immunogenetics - 1 Jan 2000

Fraile A, Collado M D, Matarán L, Martín J, Nieto A

Abstract excerpt

OBJECTIVE: HLA-B27 is strongly associated with ankylosing spondylitis (AS); however, the association is not absolute and additional susceptibility factors in the MHC region could play a role. We studied the influence of polymorphism in the transporter associated with antigen processing (TAP) genes, including point mutations not previously analyzed. METHODS: HLA-B*27 typing and subtyping as well as TAP1 and TAP2...

Topics

ATP Binding Cassette Transporter, Subfamily B, Member 2
ATP Binding Cassette Transporter, Subfamily B, Member 3
ATP-Binding Cassette Transporters
Alleles
Disease Susceptibility
Humans
Major Histocompatibility Complex
Odds Ratio
Polymorphism, Genetic
Spain
Spondylitis, Ankylosing

Source

Open in PubMed

Identifiers

PMID: 11096258
DOI: 10.1159/000019139

Genes

TAP2
TAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics