Article
TAP1 and TAP2 polymorphisms associated with ankylosing spondylitis in genetically homogenous Chinese Han population.
Human immunology - 1 Apr 2009
Feng Mingliang, Yin Biao, Shen Tong, Ma Qing, Liu Lidong, Zheng Jiewei, Zhao Yulin, Qian Kaicheng, Liu Dazhuang
Abstract excerpt
Human leukocyte antigen (HLA)-B27 is strongly associated with the autoimmune disease ankylosing spondylitis (AS). Other autoimmune disease-associated genes, such as transporter associated with antigen processing (TAP) genes, could also influence AS susceptibility. In this study, we investigated the association of TAP1 and TAP2 polymorphisms in genetically homogenous Chinese AS patients. Six TAP1 single nucleotide...
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