Article
Non-HLA genes in ankylosing spondylitis: what meta-analyses have shown?
Clinical and experimental rheumatology - 1 Jan 2000
Chatzikyriakidou Anthoula, Voulgari Paraskevi V, Drosos Alexandros A
Abstract excerpt
HLA-B27 association with ankylosing spondylitis (AS) is one of the strongest ever reported in the literature. However, only a small proportion of 5-8% of HLA-B27 positive individuals of the general population develops the disease. In recent years, polymorphisms of many non-HLA genes were reported to be associated with AS. In this review, we summarise the current knowledge of non-HLA genetic factors contributing...
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