Article
[Study on the association of transporter associated with antigen processing gene with ankylosing spondylitis and HLA-B27 in Han nationality].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Jun 2001
Wang B, Su H, Gao P, Tao L, Li X, Yie D
Abstract excerpt
OBJECTIVE: To investigate the association between transporter associated with antigen processing(TAP) gene and ankylosing spondylitis(AS) as well as HLA-B27. METHODS: PCR-SSO was used to analyze the frequencies of TAP alleles and variant amino acids of TAP in 48 patients (B27(+)) with AS and 123 normal individuals (B27(+) or B27(-)). RESULTS: The phenotypes of Ile/Ile, Asp/Asp were over-presented for TAP1 and...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 2
- ATP Binding Cassette Transporter, Subfamily B, Member 3
- ATP-Binding Cassette Transporters
- Alleles
- HLA-B27 Antigen
- Humans
- Spondylitis, Ankylosing