Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TAP1 and TAP2 polymorphism in HLA-B27-positive subpopulations: no allelic differences in ankylosing spondylitis and reactive arthritis.

Human immunology - 1 Dec 1995

Westman P, Partanen J, Leirisalo-Repo M, Koskimies S

Abstract excerpt

The polymorphic TAP1 and TAP2 genes encode subunits of the transporter that delivers peptides to the HLA class I molecules. Because the polymorphism of the TAP genes has been shown to affect peptide transport, it has been suggested that TAP genes are potential regulators of the immune response. We studied TAP1 and TAP2 polymorphism in two multifactorial HLA-B27-associated diseases, ankylosing spondylitis (N = 30)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to ATP-Binding Cassette Transporters

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to HLA-DQ Antigens

Share to HLA-DR Antigens

Share to HLA-DRB1 Chains

Share to Linkage Disequilibrium

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 8770637
DOI: 10.1016/0198-8859(95)00116-6

Genes

TAP1
TAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TAP1 and TAP2 polymorphism in HLA-B27-positive subpopulations: no allelic differences in ankylosing spondylitis and reactive arthritis.PMID 8770637Read ↗

TAP1 and TAP2 polymorphism in Spanish patients with ankylosing spondylitis.Semantic proximity Read ↗

TAP1 and TAP2 polymorphisms associated with ankylosing spondylitis in genetically homogenous Chinese Han population.Semantic proximity Read ↗

Genetic association between TAP1 and TAP2 polymorphisms and ankylosing spondylitis: a systematic review and meta-analysis.Semantic proximity Read ↗

TAP 1 and TAP 2 transporter gene polymorphisms in multiple sclerosis: no evidence for disease association with TAP.Semantic proximity Read ↗

TAP1 and TAP2 gene polymorphism in rheumatoid arthritis in a population in eastern France.Semantic proximity Read ↗

Susceptibility to Reiter's syndrome is associated with alleles of TAP genes.Semantic proximity Read ↗

Polymorphism of human major histocompatibility complex-encoded transporter associated with antigen processing (TAP) genes and susceptibility to juvenile rheumatoid arthritis.Semantic proximity Read ↗

A comparative study of HLA genes in HLA-B27 positive ankylosing spondylitis and HLA-B27 positive peripheral reactive arthritis.Semantic proximity Read ↗

Peptide transporter genes (TAP) polymorphisms and genetic susceptibility to rheumatoid arthritis.Semantic proximity Read ↗

Tap gene associations in UK caucasoids.Semantic proximity Read ↗

Analysis of the MHC-encoded transporters TAP1 and TAP2 in rheumatoid arthritis: linkage with DR4 accounts for the association with a minor TAP2 allele.Semantic proximity Read ↗

Specificities of human TAP alleles for HLA-B27 binding peptides.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.