Article
RNA aptamers as pathway-specific MAP kinase inhibitors.
Chemistry & biology - 1 Nov 2000
Seiwert S D, Stines Nahreini T, Aigner S, Ahn N G, Uhlenbeck O C
Abstract excerpt
BACKGROUND: In eukaryotic cells, many intracellular signaling pathways have closely related mitogen activated protein kinase (MAPK) paralogs as central components. Although MAPKs are therefore obvious targets to control the cellular responses resulting from the activation of these signaling pathw...
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