Article
Subunit composition of Kv1 channels in human CNS.
Journal of neurochemistry - 1 Aug 1999
Coleman S K, Newcombe J, Pryke J, Dolly J O
Abstract excerpt
The alpha subunits of Shaker-related K+ channels (Kv1.X) show characteristic distributions in mammalian brain and restricted coassembly. Despite the functional importance of these voltage-sensitive K+ channels and involvement in a number of diseases, little progress has been achieved in deciphering the subunit composition of the (alpha)4(beta)4 oligomers occurring in human CNS. Thus, the association of alpha and...
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