Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Electrophysiology and beyond: multiple roles of Na+ channel β subunits in development and disease.

Neuroscience letters - 10 Dec 2010

Patino Gustavo A, Isom Lori L

Abstract excerpt

Voltage-gated Na+ channel (VGSC) β Subunits are not "auxiliary." These multi-functional molecules not only modulate Na+ current (I(Na)), but also function as cell adhesion molecules (CAMs)-playing roles in aggregation, migration, invasion, neurite outgrowth, and axonal fasciculation. β subunits are integral members of VGSC signaling complexes at nodes of Ranvier, axon initial segments, and cardiac intercalated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Axons
Share to Cell Adhesion Molecules
Share to Ion Channel Gating

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mental Disorders

Share to Nerve Degeneration

Share to Nervous System

Share to Neurites

Share to Sodium Channels

Source

Open in PubMed Open full text

Identifiers

PMID: 20600605
DOI: 10.1016/j.neulet.2010.06.050
PMCID: PMC2964441

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Electrophysiology and beyond: multiple roles of Na+ channel β subunits in development and disease.PMID 20600605Read ↗

Na+ Channel ? Subunits: Overachievers of the Ion Channel FamilySemantic proximity Read ↗

Voltage-Gated Sodium Channel β Subunits and Their Related Diseases.Semantic proximity Read ↗

Sodium channel β subunits: emerging targets in channelopathies.Semantic proximity Read ↗

Voltage-gated Na<sup>+</sup>channels: Potential for β subunits as therapeutic targetsSemantic proximity Read ↗

Voltage-Gated Na+ Channels: Not Just for Conduction.Semantic proximity Read ↗

Beta-subunit-eliminated eHAP expression (BeHAPe) cells reveal new properties of the cardiac voltage-gated sodium channelSemantic proximity Read ↗

Beta-subunit-eliminated eHAP expression (BeHAPe) cells reveal subunit regulation of the cardiac voltage-gated sodium channel.Semantic proximity Read ↗

Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture.Semantic proximity Read ↗

Sodium channels, cardiac arrhythmia, and therapeutic strategy.Semantic proximity Read ↗

Channels active in the excitability of nerves and skeletal muscles across the neuromuscular junction: basic function and pathophysiologySemantic proximity Read ↗

Sodium channel β1 subunit localizes to axon initial segments of excitatory and inhibitory neurons and shows regional heterogeneity in mouse brain.Semantic proximity Read ↗

Sodium channels and the neurobiology of epilepsy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.