Article
Are differences in interleukin 10 production associated with joint damage?
Rheumatology (Oxford, England) - 1 Nov 2000
Huizinga T W, Keijsers V, Yanni G, Hall M, Ramage W, Lanchbury J, Pitzalis C, Drossaers-Bakker W K, Westendorp R G, Breedveld F C, Panayi G, Verweij C L
Abstract excerpt
OBJECTIVE: Constitutive differences between individuals in cytokine production may determine the variation in the course of inflammatory arthritis. METHODS: The association between interleukin 10 (IL-10) production and joint destruction was studied by comparing IL-10 mRNA content in synovial biopsies from seven patients with destructive joint disease and six patients with non-destructive joint disease. The IL-10...
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