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Article

Genetic variation in the interleukin 10 gene promoter and systemic lupus erythematosus.

The Journal of rheumatology - 1 Dec 1997

Lazarus M, Hajeer A H, Turner D, Sinnott P, Worthington J, Ollier W E, Hutchinson I V

Abstract excerpt

OBJECTIVE: To investigate interleukin 10 (IL-10) gene promoter polymorphisms in systemic lupus erythematosus (SLE) and its clinical subsets. METHODS: DNA from 76 Caucasian patients with SLE and 119 controls as genotyped for 3 defined dimorphic polymorphisms (G or A at position -1082, C or T at position -819, C or A at position -592) in the promoter region of the IL-10 gene, using the polymerase chain reaction to...

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PMID: 9415634

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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