Article
Interindividual variations in constitutive interleukin-10 messenger RNA and protein levels and their association with genetic polymorphisms.
Transplantation - 15 Mar 2003
Suárez Ana, Castro Patricia, Alonso Rebeca, Mozo Lourdes, Gutiérrez Carmen
Abstract excerpt
BACKGROUND: Genetic variations in the interleukin (IL)-10 gene promoter have been associated with levels of induced production of IL-10, disease susceptibility, and allograft rejection. Small amounts of this cytokine are constitutively produced and are important in maintaining the physiologic function of the cytokine network. In this study, we evaluated the distribution of IL-10 basal levels and its genetic...
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