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Article

Efficient expression of the tumor-associated antigen MAGE-3 in human dendritic cells, using an avian influenza virus vector.

Human gene therapy - 1 Nov 2000

Strobel I, Krumbholz M, Menke A, Hoffmann E, Dunbar P R, Bender A, Hobom G, Steinkasserer A, Schuler G, Grassmann R

Abstract excerpt

Dendritic cells (DCs) are the most potent inducers of immune reactions. Genetically modified DCs, which express tumor-associated antigens (TAA), can efficiently induce antitumor immunity and thus have a high potential as tools in cancer therapy. The gene delivery is most efficiently achieved by v...

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Share to Antigens, Neoplasm
Share to Cell Separation
Share to Gene Transfer Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Influenza A virus

Share to Luminescent Proteins

Share to Microscopy, Phase-Contrast

Share to T-Lymphocytes, Cytotoxic

Share to Transduction, Genetic

Source

Identifiers

PMID: 11084678
DOI: 10.1089/104303400750035735

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11084678-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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