Article
Efficient transduction of mature CD83+ dendritic cells using recombinant adenovirus suppressed T cell stimulatory capacity.
Gene therapy - 1 Feb 2000
Jonuleit H, Tüting T, Steitz J, Brück J, Giesecke A, Steinbrink K, Knop J, Enk A H
Abstract excerpt
We have developed a culture method for the foreign serum-free generation of highly immunostimulatory, CD83+ human dendritic cells (DC). In this study, we evaluated the feasibility and consequences of endogenously expressing antigens in mature DC using adenoviral vectors. Transduction of DC with A...
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