Article
Identification of genes with allelic imbalance on 6p associated with nasopharyngeal carcinoma in southern Chinese.
PloS one - 20 Jan 2011
Li Yan, Fu Li, Wong Alissa Michelle Go, Fan Yan-Hui, Li Miao-Xin, Bei Jin-Xin, Jia Wei-Hua, Zeng Yi-Xin, Chan Danny, Cheung Kenneth M C, Sham Pak, Chua Daniel, Guan Xin-Yuan, Song You-Qiang
Abstract excerpt
Nasopharyngeal carcinoma (NPC) is a malignancy of epithelial origin. The etiology of NPC is complex and includes multiple genetic and environmental factors. We employed case-control analysis to study the association of chromosome 6p regions with NPC. In total, 360 subjects and 360 healthy controls were included, and 233 single nucleotide polymorphisms (SNPs) on 6p were examined. Significant single-marker...
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