Article
Genetic modifiers of the insulin resistance phenotype in mice.
Diabetes - 1 Apr 2000
Kido Y, Philippe N, Schäffer A A, Accili D
Abstract excerpt
Insulin resistance can result from genetic interactions among susceptibility alleles. To identify genetic loci predisposing to insulin resistance, we used crosses between different strains of mice with a targeted null allele of the insulin receptor gene. On the genetic background of B6 mice, the...
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