Article
Gene co-expression modules and type 2 diabetes.
Results and problems in cell differentiation - 1 Jan 2010
Attie Alan D, Keller Mark P
Abstract excerpt
Although most people with type 2 diabetes are obese, most obese people never develop diabetes. They are able to compensate for the insulin resistance that usually accompanies obesity by producing more insulin. We have replicated this obesity/diabetes dichotomy in mice by studying mouse strains that differ in diabetes susceptibility when made obese with the Leptin ( ob ) mutation; the C57BL/6 (B6) mice are...
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