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Novel amplification unit at chromosome 3q25-q27 in human prostate cancer

1 Jan 2000

Abstract excerpt

BACKGROUND: In prostate carcinoma, amplification of the genes c-MYC, Her2/NEU, and the androgen receptor gene has been documented, with gene amplification being related to progressive tumor growth. Recently, using comparative genomic hybridization (CGH), we provided evidence for DNA copy number gains at chromosome 3q25-q26 in prostate cancer [Sattler et al.: Prostate 39:79-86, 1999]. METHODS: In this study,...

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PMID: 11074522
DOI: 10.1002/1097-0045(20001101)45:3<207::aid-pros2>3.0.co;2-h

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