Family with sequence similarity 13C (FAM13C) overexpression is an independent prognostic marker in prostate cancer.

doi:10.18632/oncotarget.16357

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Family with sequence similarity 13C (FAM13C) overexpression is an independent prognostic marker in prostate cancer.

Oncotarget - 9 May 2017

Burdelski Christoph, Borcherding Laura, Kluth Martina, Hube-Magg Claudia, Melling Nathaniel, Simon Ronald, Möller-Koop Christina, Weigand Philipp, Minner Sarah, Haese Alexander, Michl Hans Uwe, Tsourlakis Maria Christina, Jacobsen Frank, Hinsch Andrea, Wittmer Corinna, Lebok Patrick, Steurer Stefan, Izbicki Jakob R, Sauter Guido, Krech Till, Büscheck Franziska, Clauditz Till, Schlomm Thorsten, Wilczak Waldemar

Abstract excerpt

FAM13C, a gene with unknown function is included in several mRNA signatures for prostate cancer aggressiveness. To understand the impact of FAM13C on prognosis and its relationship to molecularly defined subsets, we analyzed FAM13C expression by immunohistochemistry on a tissue microarray containing 12,400 prostate cancer specimens. Results were compared to phenotype, ERG status, genomic deletions of 3p, 5q, 6q...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Proliferation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTPase-Activating Proteins

Share to Neoplasm Grading

Share to Neoplasm Metastasis

Share to Neoplasm Staging

Share to Oncogene Proteins, Fusion

Share to Prostatic Neoplasms

Share to Survival Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 28415558
DOI: 10.18632/oncotarget.16357
PMCID: PMC5458224

Genes

ERG
PTEN
TMPRSS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Family with sequence similarity 13C (FAM13C) overexpression is an independent prognostic marker in prostate cancer.PMID 28415558Read ↗

Recurrent deletion of 3p13 targets multiple tumour suppressor genes and defines a distinct subgroup of aggressive ERG fusion-positive prostate cancers.Semantic proximity Read ↗

MED12 overexpression is a frequent event in castration-resistant prostate cancerSemantic proximity Read ↗

Comprehensive Evaluation of TFF3 Promoter Hypomethylation and Molecular Biomarker Potential for Prostate Cancer Diagnosis and PrognosisSemantic proximity Read ↗

ERG Cooperates with Androgen Receptor in Regulating Trefoil Factor 3 in Prostate Cancer Disease ProgressionSemantic proximity Read ↗

The 16p13.3 (PDPK1) Genomic Gain in Prostate Cancer: A Potential Role in Disease ProgressionSemantic proximity Read ↗

High levels of 5-hydroxymethylcytosine (5hmC) is an adverse predictor of biochemical recurrence after prostatectomy in ERG-negative prostate cancerSemantic proximity Read ↗

Cysteine- rich secretory protein 3 (CRISP3), ERG and PTEN define a molecular subtype of prostate cancer with implication to patients’ prognosisSemantic proximity Read ↗

Clinically-observed FOXA1 mutations upregulate SEMA3C through transcriptional derepression in prostate cancer.Semantic proximity Read ↗

High-Level HOOK3 Expression Is an Independent Predictor of Poor Prognosis Associated with Genomic Instability in Prostate CancerSemantic proximity Read ↗

Dysregulation and prognostic potential of 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) levels in prostate cancerSemantic proximity Read ↗

Up regulation and nuclear translocation of Y-box binding protein 1 (YB-1) is linked to poor prognosis in ERG-negative prostate cancerSemantic proximity Read ↗

HOXB13 interaction with MEIS1 modifies proliferation and gene expression in prostate cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.