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Article

Detection of novel amplicons in prostate cancer by comprehensive genomic profiling of prostate cancer cell lines using oligonucleotide-based arrayCGH.

PloS one - 22 Aug 2007

Kamradt Joern, Jung Volker, Wahrheit Kerstin, Tolosi Laura, Rahnenfuehrer Joerg, Schilling Martin, Walker Robert, Davis Sean, Stoeckle Michael, Meltzer Paul, Wullich Bernd

Abstract excerpt

BACKGROUND: The purpose of this study was to prove the feasibility of a longmer oligonucleotide microarray platform to profile gene copy number alterations in prostate cancer cell lines and to quickly indicate novel candidate genes, which may play a role in carcinogenesis. METHODS/RESULTS AND FINDINGS: Genome-wide screening for regions of genetic gains and losses on nine prostate cancer cell lines (PC3, DU145,...

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Share to Chromosomes, Human
Share to Comparative Genomic Hybridization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to Gene Expression Regulation, Neoplastic

Share to Genome, Human

Share to In Situ Hybridization, Fluorescence

Share to Oligonucleotide Array Sequence Analysis

Share to Prostatic Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 17712417
DOI: 10.1371/journal.pone.0000769
PMCID: PMC1940319

Genes

DCTN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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