Article
Evaluation of genetic patterns in different tumor areas of intermediate-grade prostatic adenocarcinomas by high-resolution genomic array analysis.
Genes, chromosomes & cancer - 1 Mar 2004
van Dekken Herman, Paris Pamela L, Albertson Donna G, Alers Janneke C, Andaya Armann, Kowbel David, van der Kwast Theodorus H, Pinkel Daniel, Schröder Fritz H, Vissers Kees J, Wildhagen Mark F, Collins Colin
Abstract excerpt
Prostate cancer is known for its highly heterogeneous histological appearance. Data concerning the cytogenetic content of areas with different histology are sparse. We have genetically evaluated 10 prostatic adenocarcinomas with intermediate histopathological grades (Gleason score 7) that showed two distinctive growth patterns with different pathologies, that is, Gleason grades 3 and 4 (G3 and G4). The G3 and G4...
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