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Article

DNA integration by Ty integrase in yku70 mutant Saccharomyces cerevisiae cells.

Molecular and cellular biology - 1 Dec 2000

Kiechle M, Friedl A A, Manivasakam P, Eckardt-Schupp F, Schiestl R H

Abstract excerpt

In the present work we examined nonhomologous integration of plasmid DNA in a yku70 mutant. Ten of 14 plasmids integrated as composite elements, including Ty sequences probably originating from erroneous strand-switching and/or priming events. Three additional plasmids integrated via Ty integrase without cointegrating Ty sequences, as inferred from 5-bp target site duplication and integration site preferences. Ty...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 11073984
DOI: 10.1128/MCB.20.23.8836-8844.2000
PMCID: PMC86530

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Source receipt: pubmed, retrieved 7 Sept 2026.

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