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Article

Effect of rad50 mutation on illegitimate recombination in Saccharomyces cerevisiae.

Molecular genetics and genomics : MGG - 1 Jun 2011

Chan Cecilia Y, Zhu Jie, Schiestl Robert H

Abstract excerpt

Genes in the RAD52 epistasis group are involved in repairing DNA double-stranded breaks via homologous recombination. We have previously shown that RAD50 is involved in mitotic nonhomologous integration but not in homologous integration. However, the role of Rad50 in nonhomologous integration has not previously been examined. In the current work, we report that the rad50∆ mutation caused a tenfold decrease in the...

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Share to Chromosomes
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Repetitive Sequences, Nucleic Acid

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Source

Identifiers

PMID: 21512733
DOI: 10.1007/s00438-011-0619-y

Genes

RAD50
RAD52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

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Effect of rad50 mutation on illegitimate recombination in Saccharomyces cerevisiae.PMID 21512733Read ↗

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Genetic evidence for different RAD52-dependent intrachromosomal recombination pathways in Saccharomyces cerevisiae.Semantic proximity Read ↗

The effects of RAD52 epistasis group genes on various types of spontaneous mitotic recombination in Saccharomyces cerevisiae.Semantic proximity Read ↗

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The RAD50 gene, a member of the double strand break repair epistasis group, is not required for spontaneous mitotic recombination in yeast.Semantic proximity Read ↗

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