Article
Relationship between the severity of alcoholic liver cirrhosis and the metabolism of caffeine in 226 patients.
International journal of clinical pharmacology and therapeutics - 1 Oct 2000
Bechtel Y C, Haffen E, Lelouët H, Brientini M P, Paintaud G, Miguet J P, Bechtel P R
Abstract excerpt
OBJECTIVES: To evaluate the polygenic regulated caffeine metabolism in a group of 226 patients with liver alcoholic cirrhosis classified according to the Child score. METHODS: Over a 14-year period an hepatic function test, using caffeine as probe drug, has been systematically associated to the usual clinical and biochemical investigations performed in patients with liver alcoholic cirrhosis. "Caffeine test"...
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