Article
Acetylation polymorphism expression in patients before and after liver transplantation: influence of host/graft genotypes.
Pharmacogenetics - 1 Jun 1998
Bendriss E K, Bechtel Y C, Paintaud G, Brientini M P, Mantion G, Miguet J P, Bennani A, Bechtel P R
Abstract excerpt
The consequences of liver transplantation on NAT2 activity were studied in 58 patients of Caucasian origin and compared with a group control of 119 unrelated healthy individuals of the same ethnic origin. Acetylation phenotypes were determined using caffeine as a probe drug before and repeatedly after liver transplantation. NAT2 genotypes were determined with three separate polymerase chain reactions to detect...
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