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Article

A potential RNA drug target in the hepatitis C virus internal ribosomal entry site.

RNA (New York, N.Y.) - 1 Oct 2000

Klinck R, Westhof E, Walker S, Afshar M, Collier A, Aboul-Ela F

Abstract excerpt

Subdomain IlId from the hepatitis C virus (HCV) internal ribosome entry site (IRES) has been shown to be essential for cap-independent translation. We have conducted a structural study of a 27-nt fragment, identical in sequence to IlId, to explore the structural features of this subdomain. The proposed secondary structure of IlId is comprised of two 3 bp helical regions separated by an internal loop and closed at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11073218
DOI: 10.1017/s1355838200000935
PMCID: PMC1370013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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