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Article

A deletion mutation in region V of the cytomegalovirus DNA polymerase sequence confers multidrug resistance.

The Journal of infectious diseases - 1 Dec 2000

Chou S, Miner R C, Drew W L

Abstract excerpt

A patient with AIDS and cytomegalovirus (CMV) retinitis received ganciclovir and foscarnet for 20 and 5 months, respectively, with evidence of periodic disease progression. After this therapy, a CMV isolate from the patient was resistant to ganciclovir, foscarnet, and cidofovir. Sequence analysis showed a known ganciclovir resistance mutation in the viral UL97 phosphotransferase (L595F) and a new mutation in...

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Source

Identifiers

PMID: 11069251
DOI: 10.1086/317618

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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