Article
Absence of SpeB production in virulent large capsular forms of group A streptococcal strain 64.
Infection and immunity - 1 Feb 2000
Raeder R, Harokopakis E, Hollingshead S, Boyle M D
Abstract excerpt
Passage in human blood of group A streptococcal isolate 64p was previously shown to result in the enhanced expression of M and M-related proteins. Similarly, when this isolate was injected into mice via an air sac model for skin infection, organisms recovered from the spleens showed both increased expression of M and M-related proteins and increased skin-invasive potential. We show that these phenotypic changes...
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