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Article

The Secreted Esterase of Group A<i>Streptococcus</i>Is Important for Invasive Skin Infection and Dissemination in Mice

6 Oct 2009

Abstract excerpt

Virulence factors regulated by the CovRS/CsrRS two-component gene regulatory system contribute to the invasive diseases caused by group A Streptococcus (GAS). To determine whether the streptococcal secreted esterase (Sse), an antigen that protects against subcutaneous GAS infection, is one of these virulence factors, we investigated the phenotype of a nonpolar sse deletion mutant strain (Deltasse). In addition,...

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PMID: 19805529
DOI: 10.1128/iai.00636-09

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