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Article

Role of the beta isoform of 14-3-3 proteins in cellular proliferation and oncogenic transformation.

Carcinogenesis - 1 Nov 2000

Takihara Y, Matsuda Y, Hara J

Abstract excerpt

The 14-3-3 proteins are associated with proto-oncogene and oncogene products. Here, we generated NIH 3T3 cells overexpressing the beta isoform of the 14-3-3 proteins (14-3-3 beta) to examine the function of this isoform in cellular proliferation and oncogenic transformation. Overexpression of 14-3-3 beta in NIH 3T3 cells stimulated cell growth and supported anchorage-independent growth in soft agar medium and...

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PMID: 11062170
DOI: 10.1093/carcin/21.11.2073

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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