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Article

Srb7p is essential for the activation of a subset of genes.

FEBS letters - 27 Oct 2000

Gromöller A, Lehming N

Abstract excerpt

The mediator complex in the RNA polymerase II holoenzyme is known to be involved in transcriptional activation. The role of the essential mediator component Srb7p has been difficult to investigate, since no conditional lethal allele has been available to date. While the expression of Srb7p under the control of a repressible promoter is not sufficient to reduce the level of Srb7p beneath the threshold for...

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Identifiers

PMID: 11056220
DOI: 10.1016/s0014-5793(00)02123-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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