Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutations in SIN4 and RGR1 cause constitutive expression of MAL structural genes in Saccharomyces cerevisiae.

Genetics - 1 Oct 2004

Wang Xin, Michels Corinne A

Abstract excerpt

Transcription of the Saccharomyces MAL structural genes is induced 40-fold by maltose and requires the MAL-activator and maltose permease. To identify additional players involved in regulating MAL gene expression, we carried out a genetic selection for MAL constitutive mutants. Strain CMY4000 containing MAL1 and integrated copies of MAL61promoter-HIS3 and MAL61promoter-lacZ reporter genes was used to select...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha-Glucosidases
Share to Chromatin Assembly and Disassembly
Share to Gene Expression Regulation, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lac Operon

Share to Maltose

Share to Mediator Complex

Share to Monosaccharide Transport Proteins

Share to Symporters

Source

Open in PubMed Open full text

Identifiers

PMID: 15514050
DOI: 10.1534/genetics.104.029611
PMCID: PMC1448850

Genes

MAL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutations in SIN4 and RGR1 cause constitutive expression of MAL structural genes in Saccharomyces cerevisiae.PMID 15514050Read ↗

Constitutive mutations of the Saccharomyces cerevisiae MAL-activator genes MAL23, MAL43, MAL63, and mal64.Semantic proximity Read ↗

Genetic interactions between mediator and the late G1-specific transcription factor Swi6 in Saccharomyces cerevisiae.Semantic proximity Read ↗

Removal of Mig1p binding site converts a MAL63 constitutive mutant derived by interchromosomal gene conversion to glucose insensitivity.Semantic proximity Read ↗

The Ras/PKA signaling pathway of Saccharomyces cerevisiae exhibits a functional interaction with the Sin4p complex of the RNA polymerase II holoenzyme.Semantic proximity Read ↗

Identification of SAS4 and SAS5, two genes that regulate silencing in Saccharomyces cerevisiae.Semantic proximity Read ↗

Yeast genes GIS1-4: multicopy suppressors of the Gal- phenotype of snf1 mig1 srb8/10/11 cells.Semantic proximity Read ↗

A triad of subunits from the Gal11/tail domain of Srb mediator is an in vivo target of transcriptional activator Gcn4p.Semantic proximity Read ↗

A multiplicity of coactivators is required by Gcn4p at individual promoters in vivo.Semantic proximity Read ↗

Gal11 is a general activator of basal transcription, whose activity is regulated by the general repressor Sin4 in yeast.Semantic proximity Read ↗

Epistasis analysis of suppressor mutations that allow HO expression in the absence of the yeast SW15 transcriptional activator.Semantic proximity Read ↗

Genetic characterization of rbt mutants that enhance basal transcription from core promoters in Saccharomyces cerevisiae.Semantic proximity Read ↗

SWI/SNF and the histone chaperone Rtt106 drive expression of the Pleiotropic Drug Resistance network genesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.