Article
Laminins and human disease.
Microscopy research and technique - 1 Nov 2000
McGowan K A, Marinkovich M P
Abstract excerpt
The laminin protein family has diverse tissue expression patterns and is involved in the pathology of a number of organs, including skin, muscle, and nerve. In the skin, laminins 5 and 6 contribute to dermal-epidermal cohesion, and mutations in the constituent chains result in the blistering phenotype observed in patients with junctional epidermolysis bullosa (JEB). Allelic heterogeneity is observed in patients...
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