Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymerizing laminins: Assembly, functions and disorders.

Matrix biology : journal of the International Society for Matrix Biology - 1 Aug 2026

Yurchenco Peter D

Abstract excerpt

Laminins initiate basement membrane (BM) assembly by adhering to cells, establishing cytoskeletal links through integrin and dystroglycan receptors, and by polymerizing to form a sheet-like provisional matrix that recruits other BM components to complete assembly. Laminin polymerization is mediated by the LN domain tips of the three short arms that bind together to form "polymer nodes" connecting adjacent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Basement Membrane
Share to Dystroglycans
Share to Laminin

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Muscular Dystrophies

Share to Polymerization

Share to Protein Binding

Share to Protein Multimerization

Source

Identifiers

PMID: 42349693
DOI: 10.1016/j.matbio.2026.102031

Genes

LAMA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 15 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymerizing laminins: Assembly, functions and disorders.PMID 42349693Read ↗

Polymerizing laminins in development, health, and disease.Semantic proximity Read ↗

Laminin Polymerization and Inherited Disease: Lessons From GeneticsSemantic proximity Read ↗

Laminin isoforms in development and disease.Semantic proximity Read ↗

Form and function: The laminin family of heterotrimersSemantic proximity Read ↗

Laminin-deficient muscular dystrophy: Molecular pathogenesis and structural repair strategies.Semantic proximity Read ↗

Laminins and human disease.Semantic proximity Read ↗

Chimeric protein identification of dystrophic, Pierson and other laminin polymerization residues.Semantic proximity Read ↗

Chimeric protein repair of laminin polymerization ameliorates muscular dystrophy phenotype.Semantic proximity Read ↗

Functional Diversity of LamininsSemantic proximity Read ↗

A mutation affecting laminin alpha 5 polymerisation gives rise to a syndromic developmental disorder.Semantic proximity Read ↗

The laminin family.Semantic proximity Read ↗

Laminins and their roles in mammalsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.