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Article

Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains.

Journal of molecular biology - 3 Nov 2000

Dreier B, Segal D J, Barbas C F

Abstract excerpt

In order to construct zinc finger domains that recognize all of the possible 64 DNA triplets, it is necessary to understand the mechanisms of protein/DNA interactions on the molecular level. Previously we reported 16 zinc finger domains which had been characterized in detail to bind specifically to the 5'-GNN-3' family of DNA sequences. Artificial transcription factors constructed from these domains can regulate...

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Identifiers

PMID: 11054286
DOI: 10.1006/jmbi.2000.4133

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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