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Article

Association study of the 5-HTTLPR polymorphism and depression in 75-Year-Old nondemented subjects from the Vienna Transdanube Aging (VITA) study.

The Journal of clinical psychiatry - 1 Sept 2006

Grünblatt Edna, Löffler Christiane, Zehetmayer Sonja, Jungwirth Susanne, Tragl Karl-Heinz, Riederer Peter, Fischer Peter

Abstract excerpt

BACKGROUND: The site of effect for the selective serotonin reuptake inhibitors (SSRIs) is the serotonin transporter (5-HTT), which is extensively investigated for its involvement in depressive symptoms. The 5-HTT gene exhibits a 5'-promoter-based length polymorphism (5-HTTLPR) that affects the transcription efficiency and activity, known as short (S) and long (L) alleles. We studied the association of this...

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PMID: 17017823
DOI: 10.4088/jcp.v67n0907

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HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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