Article
Comparative delineation of T cell clonotypes in coexisting syngeneic B16 melanoma.
Cancer immunology, immunotherapy : CII - 1 Oct 2000
Moerch U, Schrama D, Guldberg P, Seremet T, Zeuthen J, Becker J C, thor Straten P
Abstract excerpt
B16 is a murine melanoma of C57B1/6 origin, which rapidly develops as a tumor when inoculated into syngeneic immunocompetent hosts. Nevertheless, B16 tumors are considered to be immunogenic since tumor regression can be induced by means of immunotherapeutic intervention. Furthermore, B16 melanoma cells express several melanoma-associated antigens that may serve as targets for autologous T cells. To study the in...
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