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Article

Clonotypic heterogeneity in cutaneous T-cell lymphomas.

Cancer research - 15 Oct 1990

Bignon Y J, Souteyrand P, Roger H, Fonck Y, Bernard D, Chassagne J, Ramos F, D'Incan M, Chollet P, Dastugue B

Abstract excerpt

The antigen receptor genes studied (immunoglobulin gene for B-cells, and T-cell receptor -beta or -gamma gene for T-cells) represent the most powerful tools for diagnosing the clonality of a lymphoid lineage. We have clonotyped 23 cutaneous T-cell lymphomas and 5 were found to be clonotypically all heterogeneous. Analysis of each patient was performed either from serial skin biopsies taken several months apart or...

Topics

Gene Rearrangement
Genes, Immunoglobulin
Genotype
Humans
Lymphoma, T-Cell
Receptors, Antigen, T-Cell
Skin Neoplasms

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2208124

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2208124-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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