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Article

Paraoxonase polymorphisms, pesticide exposure and Parkinson's disease in a Caucasian population.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 2000

Taylor M C, Le Couteur D G, Mellick G D, Board P G

Abstract excerpt

Parkinson's disease (PD) has been associated with exposure to pesticides and oxidative injury. The involvement of paraoxonase in both pesticide metabolism and lipid peroxidation suggests that it may play a role in the pathogenesis of PD. We examined the frequency of polymorphic alleles of the PON1 and PON2 genes in a sample of caucasian subjects with PD. The frequency distribution of these genotypes did not...

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Source

Identifiers

PMID: 11041276
DOI: 10.1007/s007020070046

Genes

PON1
PON2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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