Article
Pesticides exposure and genetic polymorphism of paraoxonase in the susceptibility of Parkinson's disease.
Acta neurologica Taiwanica - 1 Jun 2005
Fong Chin-Shih, Cheng Chun-Wen, Wu Ruey-Meei
Abstract excerpt
PURPOSE: The manifestation of Parkinson's disease (PD) is characterized by bradykinesia, resting tremor, and rigidity. The etiology of PD remains unknown. Recently several studies suggest that some environmental and genetic factors may be related to the cause of PD. Genetic variation in xenobiotic metabolizing enzymes involved in the disposition of pesticides, such as paraoxonase I (PON 1), may increase the risk...
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